William C Zamboni Selected Research

Melanoma (Melanoma, Malignant)

10/2017	Pharmacokinetics and efficacy of doxorubicin-loaded plant virus nanoparticles in preclinical models of cancer.
10/2012	Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models.
1/2012	Genetically engineered cancer models, but not xenografts, faithfully predict anticancer drug exposure in melanoma tumors.
3/2011	Tumor disposition of pegylated liposomal CKD-602 and the reticuloendothelial system in preclinical tumor models.
12/2007	Plasma, tumor, and tissue disposition of STEALTH liposomal CKD-602 (S-CKD602) and nonliposomal CKD-602 in mice bearing A375 human melanoma xenografts.
4/2004	Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma.
9/2002	Inter- and intratumoral disposition of platinum in solid tumors after administration of cisplatin.

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William C Zamboni Research Topics

Disease

69	Neoplasms (Cancer) 01/2023 - 09/2002
8	Breast Neoplasms (Breast Cancer) 10/2019 - 03/2012
8	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 02/2008
7	Melanoma (Melanoma, Malignant) 10/2017 - 09/2002
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 08/2004
5	Carcinoma (Carcinomatosis) 07/2013 - 07/2005
4	Glioma (Gliomas) 01/2020 - 07/2008
4	Ovarian Epithelial Carcinoma 03/2016 - 10/2008
3	Glioblastoma (Glioblastoma Multiforme) 04/2020 - 10/2018
2	Obesity 11/2023 - 01/2019
2	Triple Negative Breast Neoplasms 01/2021 - 11/2017
2	Diarrhea 01/2018 - 01/2004
2	Colorectal Neoplasms (Colorectal Cancer) 07/2005 - 01/2004
1	Acute Radiation Syndrome 12/2023
1	COVID-19 01/2023
1	Human Influenza (Influenza) 01/2023
1	Virus Diseases (Viral Diseases) 01/2023
1	Drug-Related Side Effects and Adverse Reactions 01/2023
1	Neoplasm Metastasis (Metastasis) 04/2020
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Endometrial Neoplasms (Endometrial Cancer) 01/2019
1	Wounds and Injuries (Trauma) 01/2017
1	Fallopian Tube Neoplasms 09/2015
1	Body Weight (Weight, Body) 01/2015
1	Inflammation (Inflammations) 04/2014
1	Hypersensitivity (Allergy) 04/2014

Drug/Important Bio-Agent (IBA)

15	Docetaxel (Taxotere)FDA Link 01/2021 - 04/2005
11	1-dodecylpyridoxal (PLD)IBA 10/2019 - 01/2012
9	liposomal doxorubicin (Doxil)FDA Link 01/2021 - 01/2013
7	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 09/2002
6	Irinotecan (Camptosar)FDA LinkGeneric 02/2016 - 01/2004
6	Carboplatin (JM8)FDA LinkGeneric 03/2012 - 01/2005
6	belotecanIBA 02/2012 - 12/2007
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2012
5	PlatinumIBA 01/2017 - 09/2002
5	rubitecanIBA 08/2008 - 08/2004
4	ChemokinesIBA 01/2020 - 10/2015
4	Cytotoxins (Cytolysins)IBA 01/2019 - 08/2005
4	CamptothecinIBA 05/2012 - 08/2004
3	LigandsIBA 12/2023 - 12/2014
3	Antineoplastic Agents (Antineoplastics)IBA 11/2023 - 12/2007
3	ClaudinsIBA 01/2021 - 10/2012
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2020 - 02/2008
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 09/2015
3	Immunoconjugates (Immunoconjugate)IBA 01/2019 - 08/2017
3	Capecitabine (Xeloda)FDA Link 01/2018 - 04/2005
3	taxaneIBA 11/2017 - 09/2006
3	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2017 - 01/2013
3	Liposomes (Liposome)IBA 01/2013 - 04/2004
3	9-aminocamptothecinIBA 08/2008 - 07/2005
3	Topotecan (Hycamtin)FDA LinkGeneric 08/2005 - 02/2003
2	gamma-glutamylaminomethylsulfonic acid (GAMS)IBA 01/2020 - 10/2018
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2020 - 10/2018
2	c-Mer Tyrosine KinaseIBA 01/2020 - 10/2018
2	Hormones (Hormone)IBA 01/2019 - 01/2016
2	Phenobarbital (Luminal)FDA Link 01/2018 - 10/2012
2	folfirinoxIBA 01/2018 - 02/2016
2	DNA (Deoxyribonucleic Acid)IBA 02/2016 - 03/2012
2	Lapatinib (GW572016)FDA Link 10/2012 - 10/2008
2	liposomal SPI-77IBA 10/2011 - 04/2004
2	lysine diisocyanate-glycerol poly(urea-urethane)IBA 09/2008 - 07/2008
2	Glycerol (Glycerine)FDA LinkGeneric 09/2008 - 07/2008
2	7- tert- butyldimethylsilyl- 10- hydroxycamptothecinIBA 09/2008 - 07/2008
2	DNA AdductsIBA 04/2004 - 09/2002
1	LipopeptidesIBA 12/2023
1	Theophylline (Theon)FDA LinkGeneric 01/2023
1	VaccinesIBA 01/2023
1	Amino Acids FDA Link 01/2023
1	CollagenIBA 01/2021
1	AcidsIBA 04/2020
1	MRX-2843IBA 01/2020
1	CytokinesIBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	Drug CarriersIBA 10/2019
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 10/2019
1	Monoclonal AntibodiesIBA 01/2019
1	Glial Fibrillary Acidic ProteinIBA 10/2018
1	UNC2025IBA 10/2018
1	Alanine Transaminase (SGPT)IBA 01/2018
1	NVP-BKM120IBA 01/2018
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2018
1	SolutionsIBA 01/2018
1	Technetium Tc 99m Sulfur Colloid FDA Link 03/2016
1	trans-sodium crocetinate (crocetin)IBA 03/2016
1	Leucovorin (Folinic Acid)FDA Link 02/2016
1	Fluorouracil (Carac)FDA LinkGeneric 02/2016
1	HydrogelsIBA 01/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2016
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 10/2015
1	Gemcitabine FDA Link 02/2015
1	Vascular Endothelial Growth Factor CIBA 12/2014
1	CC ChemokinesIBA 12/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2014
1	ProdrugsIBA 03/2014

Therapy/Procedure

17	Therapeutics 01/2023 - 01/2004
12	Drug Therapy (Chemotherapy) 01/2023 - 09/2002
1	Radiotherapy 01/2021
1	Combination Drug Therapy (Combination Chemotherapy) 02/2016
1	Precision Medicine 01/2016
1	Immunomodulation 04/2014